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AcknowledgmentsI would like to thank Prof. Mizushima and all Mizushima lab members for their guidance, support, and helpful discussions. This work is supported by Chugai Foundation for Innovative Drug Discovery Science(C-FINDs).References1. Yamamoto, H., et al. Autophagy genes in biology and disease. Nature Reviews Genetics, 24(6), 382-400 (2023).2. Zhang, S., et al. The evolution of autophagy proteins–diversification in eukaryotes and potential ancestors in prokaryotes. Journal of Cell Science, 134(13), jcs233742 (2021).j― 273 ―

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