謝辞本研究を遂行するにあたり，多大なご支援を賜りました公益財団法人 中外創薬科学財団（C-FINDs）に心より感謝申し上げます．坂根郁夫博士（千葉大学），堺弘道博士（島根大学），Kamila Dilimulati博士（千葉大学），および角田（熱田）京子氏（千葉大学）には，本研究に関して多大なご助言とご協力をいただきました．ここに深謝の意を表します．引用文献1. Murakami, C., and Sakane, F. (2021) Sphingomyelin synthase-related protein generates diacylglycerol via the hydrolysis of glycerophospholipids in the absence of ceramide J. Biol. Chem., 100454 10.1016/j.jbc.2021.1004542. Murakami, C., Hoshino, F., Sakai, H., Hayashi, Y., Yamashita, A., and Sakane, F. Diacylglycerol kinase delta and sphingomyelin synthase-related protein functionally interact via their sterile alpha motif domains J. Biol. Chem. 295, 2932-2947 (2020). 10.1074/jbc.RA119.0123693. Taniguchi, M., and Okazaki, T. Ceramide/Sphingomyelin Rheostat Regulated by Sphingomyelin Synthases and Chronic Diseases in Murine Models J. Lipid Atheroscler 9, 380-405 (2020). https://doi.org/10.12997/jla.2020.9.3.3804. Suzuki, R., Murakami, C., Dilimulati, K., Atsuta-Tsunoda, K., Kawai, T., and Sakane, F. Human sphingomyelin synthase 1 generates diacylglycerol in the presence and absence of ceramide via multiple enzymatic activities FEBS Lett. 597, 2672-2686 (2023). 10.1002/1873-3468.147355. Murakami, C., Dilimulati, K., Atsuta-Tsunoda, K., Kawai, T., Inomata, S., Hijikata, Y. et al. Multiple activities of sphingomyelin synthase 2 generate saturated fatty acid- and/or monounsaturated fatty acid-containing diacylglycerol J. Biol. Chem. 300, 107960 (2024). 10.1016/j.jbc.2024.1079606. Sakai, H., Kado, S., Taketomi, A., and Sakane, F. Diacylglycerol kinase δ phosphorylates phosphatidylcholine-specific phospholipase C-dependent, palmitic acid-containing diacylglycerol species in response to high glucose levels J. Biol. Chem. 289, 26607-26617 (2014). 10.1074/jbc.M114.5909507. Furuta, M., Murakami, C. Numagami, Y., Suzuki, R., and Sakane, F. Diacylglycerol kinase zeta interacts with sphingomyelin synthase 1 and sphingomyelin synthase-related protein via different regions FEBS Open Bio 13, 1333-1345 (2023). 10.1002/2211-5463.13628― 129 ―
元のページ ../index.html#131