中外創薬 助成研究報告書2023
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― 258 ―2. Yamamoto K*# (*筆頭著者、#責任著者), Iwadate D, Kato H, Nakai Y, Tateishi K, Fujishiro M: Targeting autophagy as a therapeutic strategy against pancreatic cancer. J Gastroenterol, 57 (9), 603-618 (2022).3. Yamamoto K*# (*筆頭著者、#責任著者), Iwadate D, Naito E, Tateishi K, Fujishiro M: Autophagy as a critical driver of metabolic adaptation, therapeutic resistance, and immune evasion of cancer. Current Opinion in Biotechnology, 84, 103012 (2023) 4. Kato H, Tateishi K, Fujiwara H, Nakatsuka T, Yamamoto K, Kudo Y, Hayakawa Y, Nakagawa H, Tanaka Y, Ijichi H, Otsuka M, Iwadate D, Oyama H, Kanai S, Noguchi K, Suzuki T, Sato T, Hakuta R, Ishigaki K, Saito K, Saito T, Takahara N, Kishikawa T, Hamada T, Takahashi R, Miyabayashi K, Mizuno S, Kogure H, Nakai Y, Hirata Y, Toyoda A, Ichikawa K, Qu W, Morishita S, Arita J, Tanaka M, Ushiku T, Hasegawa K, Fujishiro M, Koike K: MNX1-HNF1B Axis Is Indispensable for Intraductal Papillary Mucinous Neoplasm Lineages. Gastroenterology, 162 (4), 1272-1287.e16 (2022).謝 辞本研究を遂行するにあたり,多大なご支援を賜りました公益財団法人 中外創薬科学財団に心より感謝申し上げます.引用文献1. Yamamoto K* (*筆頭著者), Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC: Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature, 581 (7806), 100-5 (2020).

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